Chaperone相关论文
Mitochondria,double-membrane organelles,are known to participate in a variety of metabolic and signal transduction pathw......
Dysfunctional sperm maturation is the primary reason for the poor sperm motility and morphology in infertile men.Spermat......
Nanogels can be used as new biologics DDS by efficiently trapping biomacromolecules within the network.We first reported......
The E3 ubiquitin ligase CHIP mediates ubiquitination and proteasomal degradation of PRMT5 during ost
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Chaperone heat shock protein 70 modulators dual-regulate the development of behavioral sensitization
Aim: Our previous studies have revealed behavioral sensitization, closely relating to drug addiction, mediated by chaper......
Modulating Stat1 signaling by mitochondrial Tid1-a human homolog of bacterial DnaJ and the Drosophil
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SurA and Skp are both periplasmic chaperones in the biogenesis of E.coli β–barrel outer membrane proteins(OMPs).......
The heat-shock protein DegP is essential for the survival of Escherichia coli cells at elevated temperatures.Substrate b......
DegP belongs to the HtrA family.As a heat-shock-like protein, DegP is said to have protease/chaperone dual function and ......
Modulating Stat1 signaling by mitochondriai Tid1-a human homolog of bacterial DnaJ and the Drosophil
Human Tidl is a human homolog of bacterial DnaJ and the Drosophila tumor suppressor Tid56 that have two alternatively sp......
The heat-shock protein DegP is essential for the survival of Escherichia coli cells at elevated temperatures.Substra......
Small heat shock proteins (sHSPs) exist ubiquitously among all organisms, with a variety of functions. All small heat sh......
α-晶状体蛋白是眼晶状体细胞质的主要成分,由小热休克蛋白家族中的αA-晶状体蛋白和αB-晶状体蛋白组成.α-晶状体蛋白具有分子伴......
乙型肝炎病毒(Hepatitis B virus,HBV)是引起肝炎疾病的主要因素。HBV自身基因组极其简单,病毒复制生命过程都是在宿主因子协同作......
目的检测并分析幽门螺杆菌(Hp)尿素酶β亚基(UreB)与Hsp60之间的相互作用。方法克隆Hp 26695的尿素酶β亚基基因(UreB)融合GST标签......
Gene cloning and sequence analysis of the cold-adapted chaperones DnaK and DnaJ from deep-sea psychr
本文通过对荣华二采区10...
Heat shock proteins (Hsps) or molecular chaperones,are highly conserved protein families present in all studied organism......
As a large family of hydrolases,GTPases are widespread in cells and play the very important biological function of hydro......
,Cytosolic HSP90 Cochaperones HOP and FKBP Interact with Freshly Synthesized Chloroplast Preproteins
Most chloroplast and mitochondrial proteins are synthesized in the cytosol of the plant cell and have to be imported int......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
主细胞、变性CS复性及EB感染宿主细胞形成包涵体中的作用.结果 EB与宿主细胞接触前与重组融合蛋白DsbG作用30 min后,吸附宿主细胞......
Objective Pseudomonas aeruginosa is a ubiquitous and opportunistic pathogen that uses the type III secretion system (TTS......
Molecular chaperones are able to interact with unfolded states of the protein molecule preventing their aggregation and ......
MHCⅠ类分子在内质网中组装形成肽-MHC复合体.抗原肽主要来自于胞内蛋白,在蛋白酶体作用下形成的8～10个氨基酸小肽.内质网中的多个......
当生物面临各种病理及环境压力胁迫时,细胞内的分子伴侣能够辅助蛋白质的正确折叠。近年来的研究表明,分子伴侣如Hsp70和Hsp90的生......
分子伴侣ＳｅｃＢ基因和人淋巴毒素基因在大肠杆菌中的共表达周颖张青殷长传宋大新陈永青（复旦大学微生物学系和遗传研究所上海２００４３３）分子......
Objective Pseudomonas aeruginosa is a ubiquitous and opportunistic pathogen that uses the type III secretion system (TTS......
本文总结了近十年有关热休克蛋白在动物胚胎发育中动态变化的研究成果，并讨论了热休克蛋白在歪胎发育中可能作用。......
目的分析前列腺癌细胞的热休克蛋白70(HSP70)表达情况及其与前列腺癌的发生、发展及治疗的关系.方法细胞免疫化学染色. 结果前列腺......
目的研究预缺血对蛋白伴侣hsp70表达和蛋白聚集物形成的影响，探讨其可能的脑保护机制。方法采用大鼠双侧颈总动脉暂时夹闭法建立全......
目的：探索定位于细胞质、内质网膜及内质网腔中的分子伴侣及其组合对于带有不同信号肽的胞外β-1，3-葡聚糖酶（EXGl）在巴斯德毕赤酵母GS......
很多革兰氏阴性致病菌使用Ⅲ型分泌系统(type Ⅲ secretion system,TTSS)将毒力因子直接注射到宿主细胞质中,其中某些效应蛋白(即......
目的筛查细胞质基质中组蛋白H2A变体macro H2A的分子伴侣,借此研究macro H2A在分子伴侣的协助下进入细胞核的分子机制。方法建立在......
通常，错误折叠的和未折叠的蛋白质通常在chaperone（伴侣蛋白）的辅助下重新折叠或在26S蛋白酶体的作用下降解。这些蛋白质也可能通过聚......
Antigen containing, allogeneic cells secreting the genetically modified protein and peptide-chaperone gp96-Ig cross, pri......
Ⅲ型分泌系统广泛存在于革兰氏阴性致病菌中.通过Ⅲ型分泌系统,耶尔森氏菌属、沙门氏菌属、福氏志贺氏菌等革兰氏阴性致病菌注射毒......
a-Crystallin is the major structural protein of eye lens of vertebrates. In human lens, the ratio of aA-crystallin to aB......
Cytosolic chaperonin CCT (also known as TRiC) is a hetero-oligomeric cage-like molecular chaperone that assists in prote......
Introduction: As a chaperone, heat shock protein acts as central integrators of protein homeostasis in cell. The form of......
Introduction: As a chaperone, heat shock protein acts as central integrators of protein homeostasis in cell. The form of......
GroESL protects superoxide dismutase (SOD)— Deficient cells against oxidative stress and is a chaper
Superoxide dismutase (SOD)-deficient Escherichia coli OX326Acells are protected against chemically-induced oxidative str......
目的研究新生霉素（novobiocin，NB）对K562细胞的作用，并探讨该作用是否与热休克蛋白90（Heatshockprotein90，Hsp90）分子伴侣的功能有关。方......
DnaK is implicated in protein folding, repair and degradation. Its protective role during heat shock is well documented ......
Pseudoalteromonas sp.SM9913 is a phychrotrophic bacterium isolated from the deep-sea sediment.The genes encoding chapero......
<正>帕金森病（PD）在最常见的神经变性疾病中排在第二位,临床表现为静止性震颤、动作性僵直,主要是由于大脑致密层的黑质多巴胺能神经......
AAA+ ClpB chaperone as a potential virulence factor of pathogenic microorganisms: Other aspect of it
We describe and discuss the most recent findings on the activity and function of the oligomeric AAA+ chaperone ClpB from......
Heat shock protein (HSP) is a kind of protein that mainly acts as a molecular chaperone to participate in the synthesis ......
通过过量表达大肠杆菌分子伴侣ＳｅｃＢ和ＧｒｏＥＬ，研究了它们对靶蛋白的分泌及可溶性的影响，在过量表达ＳｅｃＢ的宿主菌中，周质空间分泌蛋白总量较对照组提高......
